KMID : 0363220180560010030
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Korean Journal of Dermatology 2018 Volume.56 No. 1 p.30 ~ p.35
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Comorbid Autoimmune Diseases among Patients with Alopecia Areata: A Population-based Case-control Study in Korea
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Han Sung-Soo
Seo Hyun-Min Kim Joung-Soo
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Abstract
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Background: There have been few studies on the association between alopecia areata (AA) and its comorbidities.
Objective: The purpose of this study was to investigate the association and incidence of autoimmune diseases related to alopecia areata in Koreans using National health insurance service database.
Methods: This study was a retrospective case-control study based on the National Health Insurance Service-National Sample Cohort database of patients with AA and age- and sex-matched control subjects from 2003 to 2013.
Results: Among 12,199 patients with AA and 60,995 control subjects, patients with AA were at significantly increased risk for Graves¡¯ disease, Hashimoto¡¯s thyroiditis, vitiligo, psoriasis, lupus erythematosus, and rheumatoid arthritis compared to control subjects.
Conclusion: The risk of various autoimmune diseases was significantly increased in patients with AA.
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KEYWORD
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Alopecia areata, Autoimmune disease, Thyroid disease
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